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Prebiotic fibers support the health of the gut microbiota among those with functional GI disorders, such as IBS. Research highlights their mechanistic ability to increase beneficial short-chain fatty acids and manage inflammation, but the impact of prebiotic fiber supplementation on symptom relief varies. Although supplementation shows promise, caution is advised when introducing prebiotics in IBS patients due to their potential to exacerbate symptoms.

New Partnership between digestive health brands delivers evidence-based, holistic support to the irritable bowel syndrome community.

Ongoing research continues to unveil the complex ways in which the gut microbiota play a role in IBS onset and symptoms. While there is no single ideal composition of gut microbiota that defines a “healthy” composition, there are general strategies that can support a strong and robust Gut-Brain-Microbiota Axis.

The connection between the brain and the gut has long been recognized and, more recently, research has shed light on the nuanced mechanisms that govern this gut-brain communication and the crucial role played by gut microbiota. These findings provide valuable insights into communication pathways, their role in the pathophysiology of IBS, and implications for symptom management.

While categorized as a digestive disorder, Irritable Bowel Syndrome (IBS) affects far more than the digestive tract. The most common symptoms of IBS include abdominal pain, bloating, constipation, and diarrhea, all of which not only cause physical discomfort, but also have a significant impact on a quality of life and mental health.

While a balanced diet remains a cornerstone in promoting digestive function, current understanding of the gut-brain axis highlights the important role sleep, exercise, stress, and other psychological factors play in maintaining GI homeostasis.

Recent studies seek to assess how probiotic, prebiotic, fermented foods, polyphenols and foods with resistant starch may support increased abundance and resilience of beneficial (commensal) microbes in patients with dysbiosis, though evidence to support their use remains limited to date.

A large focus in the treatment of IBS and other gastrointestinal conditions is regulation of intestinal permeability and promotion of intestinal barrier function.

IBS is a complex condition with diverse symptoms. A so-called trifecta of root causes is proposed as the source of most symptoms: dysbiosis, inflammation, and leaky gut. Dietary interventions, like the low FODMAP diet, may promote a healthy microbiome, reduce inflammation, and ease digestive symptoms. Supplements and digestive enzymes may also be warranted to remove pathogenic bacteria and promote intestinal repair.